AMD Instinct MI325X vs AMD Instinct MI350X
AI GPU comparison · AMD vs AMD · 2024 vs 2025
AMD Instinct MI325X vs AMD Instinct MI350X — head to head
| Metric | AMD Instinct MI325X | AMD Instinct MI350X |
|---|---|---|
| Relative tier | 96/100 | 98/100 |
| TDP / power | 1000 W | 1200 W |
| Memory | 256 GB | 288 GB |
| Bandwidth | 6000 GB/s | 6600 GB/s |
| Boost clock | 2100 MHz | 2000 MHz |
| FP16 compute | 1307 TFLOPS | 1460 TFLOPS |
Which one should you pick?
The two are within ~2 tier points of each other, so the relative-performance index does not clearly separate them. 288 GB VRAM on the larger card vs 256 GB. Tier is a TweakGearPro planning estimate, not a benchmark — verify with reviews that match your exact workload, resolution and workload mix before buying.
Specs: vendor datasheets / TechPowerUp database, retrieved 2026-08-29. Tier is a TweakGearPro relative performance index (estimate), not a benchmark guarantee.
Full specifications
AMD Instinct MI325X
| Brand / series | AMD Instinct MI325 |
|---|---|
| Architecture / class | CDNA 3 |
| Launch year | 2024 |
| Memory | 256 GB HBM3e · 8192-bit · 6000 GB/s |
| Boost clock | 2100 MHz |
| FP16 compute | 1307 TFLOPS |
| FP8 compute | 2614 TFLOPS |
| Interconnect | Infinity Fabric |
| TDP | 1000 W |
| Relative tier | 96/100 — Enthusiast flagship |
AMD Instinct MI350X
| Brand / series | AMD Instinct MI350 |
|---|---|
| Architecture / class | CDNA 4 |
| Launch year | 2025 |
| Memory | 288 GB HBM3e · 8192-bit · 6600 GB/s |
| Boost clock | 2000 MHz |
| FP16 compute | 1460 TFLOPS |
| FP8 compute | 2920 TFLOPS |
| Interconnect | Infinity Fabric |
| TDP | 1200 W |
| Relative tier | 98/100 — Enthusiast flagship |