H200 SXM 141GB vs AMD Instinct MI350X
AI GPU comparison · NVIDIA vs AMD · 2024 vs 2025
H200 SXM 141GB vs AMD Instinct MI350X — head to head
| Metric | H200 SXM 141GB | AMD Instinct MI350X |
|---|---|---|
| Relative tier | 97/100 | 98/100 |
| TDP / power | 700 W | 1200 W |
| Memory | 141 GB | 288 GB |
| Bandwidth | 4800 GB/s | 6600 GB/s |
| Boost clock | 1980 MHz | 2000 MHz |
| FP16 compute | 989 TFLOPS | 1460 TFLOPS |
Which one should you pick?
The two are within ~1 tier points of each other, so the relative-performance index does not clearly separate them. 288 GB VRAM on the larger card vs 141 GB. Tier is a TweakGearPro planning estimate, not a benchmark — verify with reviews that match your exact workload, resolution and workload mix before buying.
Specs: vendor datasheets / TechPowerUp database, retrieved 2026-08-29. Tier is a TweakGearPro relative performance index (estimate), not a benchmark guarantee.
Full specifications
H200 SXM 141GB
| Brand / series | NVIDIA Datacenter Hopper |
|---|---|
| Architecture / class | Hopper |
| Launch year | 2024 |
| Memory | 141 GB HBM3e · 6144-bit · 4800 GB/s |
| Boost clock | 1980 MHz |
| FP16 compute | 989 TFLOPS |
| FP8 compute | 1979 TFLOPS |
| Interconnect | NVLink 4 / SXM5 |
| TDP | 700 W |
| Relative tier | 97/100 — Enthusiast flagship |
AMD Instinct MI350X
| Brand / series | AMD Instinct MI350 |
|---|---|
| Architecture / class | CDNA 4 |
| Launch year | 2025 |
| Memory | 288 GB HBM3e · 8192-bit · 6600 GB/s |
| Boost clock | 2000 MHz |
| FP16 compute | 1460 TFLOPS |
| FP8 compute | 2920 TFLOPS |
| Interconnect | Infinity Fabric |
| TDP | 1200 W |
| Relative tier | 98/100 — Enthusiast flagship |